Javanese Ginseng Root Extract (Talinum Paniculatum (Jacq) Gaertn) to Increase Superoxide Dismutase Activities in White Male Sprague Dawley Rats by Using a Forced Swimming Test Model

Continuously performing heavy activities will damage tissues and cells cause oxidative stress. Fortunately, this can be reduced by giving antioxidants to reduce free radicals. This study uses the forced swimming test model determine effect of Javanese ginseng root extract on superoxide dismutase levels in male white Sprague Dawley rats. The samples were 30 rats divided into five groups: negative control group, positive treatment group 1 receiving at a dose 0.35mg/200g BW/day, 2 0.70mg/200g 3 1.4mg/200g BW/day. On days 28 35, treated with FST model. Meanwhile, SOD measured using xanthine-xanthine oxidase method. was analyzed statistical analysis. administration doses 0.35 mg/200g BW rats/day, 1.40 rats/day could significantly increase (p < 0.05). level up normal give same as xanthine > 0.05) does. In conclusion, increases suggests potential natural-based antioxidant supplement investigating human subjects, especially athletes bodybuilders